Striga species, the so-called witchweeds, are widespread in semi-arid areas of eastern and southern Africa. These parasitic plants can reduce sorghum yields by up to 80%, causing hardship to some of the poorest farmers in the region. Two Striga-tolerant varieties of sorghum have been identified and their yields in trials were superior to those from previously available cultivars. These varieties have been approved for release by the Tanzania seed registration authority and are now in use. This article also guides farmers on which cultivar to plant according to soil types and the type of fertiliser to use.